© Kamla-Raj 2005                                                                    Int J Hum Genet, 5(2): 153-163 (2005)

 

 

Polymorphisms of Q-band Heterochromatin: Qualitative and

Quantitative Analyses of Features in 3 Ethnic Groups

(Europeans, Indians, and Turks)

 

L. Kalz, B. Kalz-Füller, S. Hegde* and G. Schwanitz

 

Institute for Human Genetics, Bonn, Germany

*Manipal Hospital, Bangalore, India

 

Keywords Human constitutive heterochromatin; fluorescence polymorphisms i(5); population genetics; European, Indian, and Turkish genetic relations; chromosome-specific polymorphisms; heterochromatin in acrocentric chromosomes.

 

Abstract Focusing predominantly on fluorescence polymorphisms i(5) after QFQ-banding and some CBG – banding in lymphocyte cultures, the comparison of polymorphisms of constitutive heterochromatin in the chromosomes 1, 3, 4, 9, 13, 14, 15, 16, 21, 22, and Y of Central Europeans with those of Indians and Turks showed insignificant differences in the sizes vs and m but significant differences in the size s with the highest number in the Indian group. Differences in fluorescence i(5) proved to be statistically highly significant among the 3 groups as well as differences in the duplication of the satellite stalk (p12) of the acrocentric chromosomes. The number of fluorescence i(5) per case was highest in the Indian and lowest in the Turkish group. The comparison of polymorphisms revealed the least number of differences to exist between Europeans and Indians, followed by Europeans and Turks, with Turks and Indians having the highest number of significant differences.

 


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