© Kamla-Raj 2001                                                                       Int J Hum Genet, 1(4): 301-302 (2001)

Translocation (9;10) Pat, in a Male Child Leading to Monosomy
9p13à9pter and Trisomy 10q24à10qter

I.M. Thomas¹, M. Neelamma, K.S. Reddy², B.G. Gopalkrishna³ and

Sayee Rajangam¹

1.  Division of Human Genetics, Department of Anatom, St. John's Medical College, Banglore 560 034, Karnataka, India
2. Quest's Center for Diagnostic Innovation, 33608, Ortega Highway, San Juan, Gaplstrana, California, 92960, USA

3. Department of Pediatrics St. Martha's Hospital Bangalore 560 009,

Karnataka, India

Key Words Familial t(9;10); multiple congenital anomalies; monosomy 9p13à9pter, trisomy 10q24à10qter.

Abstract  A rare case of paternal/familal translocation (9;10) leading to monosomy 9p13à9pter  and trisomy 10q24à10qter in a 3 month old male child born with multiple congenital anomalies is reported.  Family studies revealed the presence  of balanced translocation (9;10) in father, paternal grandmother, three paternal aunts and a paternal cousin.

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